Juan Gaertner

Juan Gaertner

I'm a graduate chemist and 3d-artist specialized in scientific visualisation and animation.
德国
德国

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426 张库存照片、矢量图和插图可免版税使用。

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Candida yeasts. C. albicans and C. auris are two pathogenic yeasts that cause candidiasis. C. auris has acquired multiple drug resistance. It's infection can end deadly.  3d rendering
阿尔茨海默病:淀粉样-β 肽积累到淀粉样纤维,积聚致密淀粉样斑块。3d 渲染
RNA polymerase is composed of several proteins. It unwinds DNA strands (violet) and builds RNA (red) out of the nucleotides uridine, adenosine, cytlidine and guanosine monophosphate. 3d rendering
After activation by antigen presenting cells, T helper cells segregate several cytokins IL-4, IL-5, IL-6, IL-9, IL-10 and IL-13, Source: PDB entries 2B8U, 3VA2, 1ALU, 2H24, 3BPO, 3d rendering
The insulin receptor (blue) is a transmembrane protein, that is activated by insulin (orange) These leads to the transport of glucose into the cell mediated by a glucose tranporter (red). 3d rendering
Proteasome degrading a protein (red) tagged with polyubiquitin.  They degrade unneeded or damaged proteins that have been tagged with polyubiquitin (yellow). Source PDB entry 5GJQ. 3d rendering
The coronavirus spike protein (red) mediates the virus entry into host cells. It binds to the angiotensin converting enzyme 2 (blue) and fuses viral and host membranes. PDB entry 6cs2. 3d rendering
A microglia cell. It plays an important role in the pathogenesis of Alzheimer's disease. Microglia are specialised macrophages that restrain the accumulation of amyloid plaques (orange). 3d rendering
Insulin molecules. Insulin is a protein hormone that regulates the metabolism of carbohydrates and fats.   3d rendering
Petase 是一种细菌酶,可将宠物-塑料分解为单体分子。 整个细菌降解过程产生无害环境的产品。3d 渲染
Alzheimer's disease: Pathological Tau protein (red-orange) phosphorylation (yellow) leads to disintegration of microtubuli and aggregation to neurofibrillary tangles (orange) in a neuron axon.
Insulin receptor inactivated, insulin is close to the binding site. Insulin binding activates a signal cascade leading to the transport of glucose into the cell. 3d rendering
Activation of the immune response: antigen presenting cell activates T-lymphocytes (smaller  cells).  Magnification: T-cell receptor in complex with an MHC class II molecule and an antigen. 3d renderi
 Insulin (orange) bound to the insulin receptor (blue). Insulin binding induces structural changes within the receptor leading to the transport of glucose molecules into the cell. 3d rendering
The calcitonin gene related peptide (yellow) binds to its receptor (blue) on neurons and smooth muscle cells of cerebral blood vessels that  leads to a dilatation of the blood vessels, 3d rendering
Candida albicans can become pathogenic in immunocompromised persons. It causes the infection candidiasis. It's one of the most common hospital acquired infections. 3d rendering
Microglia cells (red) play an important role in the pathogenesis of Alzheimer's disease. Microglia are specialised macrophages that restrain the accumulation of amyloid (orange plaques). 3d rendering
绦虫在人类肠道。3D 渲染。
绦虫是寄生扁虫的一种。 他们生活在脊椎动物的消化道。
MDM2 (violet) controls the action of p53 tumor suppressor (blue), which cannot bind to DNA and trigger the self-destruction of the cell. Ubiquitin (yellow)  targets p53 for destruction. 3d rendering
The voltage-gated ion channel  iscomposed of a large alpha subunit and one or more regulatory beta subunits (dark blue). Source: PDB entry 6AGF. 3d rendering
Interleukin 13 binds to the IL-13-receptor. It is a mediator of allergic inflammation and different diseases including asthma, mucus hypersecretion, fibrosis, airway hyperresponsiveness. 3d rendering
结肠受溃疡性结肠炎影响,3d 渲染。
溃疡性结肠炎是人肠的炎症性疾病。
Chimeric antigen receptor therapy,
CAR molecules (light blue) bind to CD19 molecules on a leukemia cell leading to segregation of granzyme vesicles (yellow) that activate the apoptosis, 3d rendering
Large roundworm in human intestine.
Ascaris lumbricoides lives in the intestines.The larvae penetrate the intestine wall, enter the blood stream and infestate several organs. 3d rendering
After activation by an antigen presenting cell, a T helper cell segregates the cytokines IL-4, IL-5, IL-6, IL-9. IL-10 and IL-13. Source: PDB entries 2B8U, 3VA2, 1ALU, 2H24, 3BPO. 3d rendering
Insulin receptor inactivated (left) and activated (right), after insulin binding. Insulin binding activates a  signal cascade leading to the transport of glucose into the cell. 3d rendering
肠道受摩尔布斯克罗恩影响. 3d 渲染.
克罗恩氏病是一种炎症性肠疾病,它会导致腹痛,腹泻和呕吐。
CRISPR-Cas9: The Cas9 enzyme in complex with RNA (yellow) and single stranded DNA (violet). It is used as a specific and easy way to edit genes. Source: PDB entry 5b2r. 3d rendering
Pyramidal neurons in the cerebral cortex. Pyramidal neurons 
are found in certain areas of the brain including the cerebral cortex, the hippocampus, and the amygdala. 3d rendering
Microglia cell and neuron. Microglial cells are specialised macrophages. They are constantly scavenging the central neuron system for plaques, damaged neurons and infectious agents. 3d rendering
绦虫在人肠,放大头部连接到肠道。3D 渲染。
绦虫是寄生扁虫的一种。 他们生活在脊椎动物的消化道。
Activation of a Ras protein
Inactive Ras protein (left) is activated by a GEF protein opening the binding site allowing GDP to exit. Then GTP can bind to RAS turning it into the active form. 3d render
血浆细胞(B 细胞)分离特异性抗体,以标记随后破坏病毒(流感病毒).3D 渲染。

Membrane proteins involved in  the activation and inhibition of the immune system through the interaction of antigen presenting cells and T-cells. 3d rendering
T-cell receptor, CD-4, CD-28, PD-1 and CTLA-4 and a calcium channel on a T-cell 
TCR (blue), CD-4 (light blue), CD-28 (dark blue),  PD-1 (magenta), CTLA-4 (violet), Ca-channel (violet), 3d rendering
Tapeworm head attached to the intestine. 3D rendering.
Tapeworms are a species of parasitic flatworms. They live in the digestive tracts of vertebrates.
Multiple sclerosis (MS): heatlhy neuron with intact myelin sheaths (left), neuron affected by MS (right) 
Microglia cells attack the oligodendrocytes that form the  myelin sheath. 3d rendering
淋巴细胞攻击的癌细胞
Different structures of membrane proteins: (left to right) Potassium channel, delta-opioid receptor, LDL receptor, acetylcholine receptor, histamine receptor, 3d rendering
T 淋巴细胞和树突状细胞,3D 渲染;
树突状细胞是免疫系统的抗原呈现细胞。 他们处理抗原材料,并将其呈现在细胞表面的 T 细胞。
Activated Ras protein attached to the cell membrane. Ras proteins tansmit signals within cells  turning on genes involved in cell growth, differentiation. Mutations can lead to cancer. 3d Rendering.
The chemokine receptor 5 with a bound antagonist.The HIV1-coreceptor CCR5, is an attractive target  for preventing the entry of human immunodeficiency virus. Source: PDB entry 4mbs. 3d rendering
THC 分子与大麻素受体结合。 受体主要出现在神经系统中,并参与食欲,疼痛感,情绪和记忆。3d 渲染
在骨髓中划分干细胞,3D 渲染
Borrelia infection in the blood. Borrelia bacteria cause borreliose, transmitted by ticks and by lice. 3ds rendering
Antibody.
Antibodies are proteins produced by plasma cells. They identifiy and neutralize bacteria and viruses. Antibodies recognize unique molecules of the pathogen, called antigens. 3d rendering
内脏脂肪是高度激素活跃。3d 渲染
结直肠癌。3d 渲染。
健康的肠道。3D 渲染。
The SARS-CoV-2 RNA dependent RNA polymerase is a promising target for the treatment of COVID-19. R2Rp is an enzyme that catalyzes the replication of RNA from an RNA template. PDB 7BTF. 3d rendering
Ras activation
Inactive Ras protein (left) is activated by a GEF protein opening the binding site and allowing GDP to exit. GTP can now bind to RAS turning it into the active form(right). 3d rendering
胰岛素分子
胰岛素是一种蛋白质,通过葡萄糖的同化调节碳水化合物和脂肪的新陈代谢。 胰岛素二聚体:来源:PDB 条目 1TRZ。3D 渲染
血流中的 LDL 粒子低密度脂蛋白(LDL)颗粒将血浆中的水不溶性脂质从肝脏传输到其他器官和组织。
脊椎椎椎间盘突出
Dehalogenases: bacterial enzymes can destroy halogenated environmental pollutants. The active site is highlighted. 3d rendering
相间细胞核的视图(DNA、mRNA、核仁和几种酶)
背影。3d 渲染。
在大肠里的水肺。 这些水肺中的一个发炎的结果。 最常见的症状是腹痛。
干细胞
低密度脂蛋白(LDL)的结构
蛋白 ApoB 100(蓝色),磷脂(橙色与蓝色帽),胆固醇(橙色与紫色帽),甘油三酯和胆固醇酯(黄色)
Dendritic cell. 3D-rendering.
Dendritic cells  are antigen-presenting cells  of the immune system.
Macrophag engulfing bacteria (cocci), 3D rendering.
Macrophages engulf and digest cellular debris and pathogens.
White matter in the brain and spinal cord: neurons with myelinated axons, oligodendrocytes forming the myelin sheaths, fibrous astrocytes (dark blue) and microglia cells (violet). 3d rendering
Lymphocytes in the blood
阿尔茨海默病:神经元与淀粉样斑块,
High density lipoprotein (HDL)
color code: protein ApoA (green), phospholipids (orange with a blue cap), cholesterol (orange with a violet cap)
Dividing cancer cell
3 phases of the Alzheimer disease.
1. Healthy neuron. 2. Neuron with amyloid plaques (yellow). 3. Dead neuron being digested by microglia cells (red)
Carboniferous forest
p53 bound to DNA
p53 prevents cancer formation and acts as a guardian of the genome. Mutations in the p53 gene contribute to about half of the cases of human cancer. 3d rendering
Alzheimer disease, neuron network with amyloid plaques
脂肪细胞,3D 渲染。
白色脂肪细胞含有一个大的脂质液滴(黄色)和一个核(红色)位于外围。
Arteriosclerosis (4 phases)
Candida auris causes candidiasis, an infection of the bloodstream, the central nervous system and internal organs. It has acquired multiple drug resistance. 3d rendering
Antibiotic (streptomycin) molecules being expelled out of a bacterium through the TolC efflux-pump. 3d rendering.
癌细胞和淋巴细胞
Oligodendrocyte forms insulating myelin sheaths around neuron axons in the central nervous system. Myelin increases the impulse speed and decreases the capacitance of the axon membrane. 3d rendering
Macrophages approaching bacteria (bacilli), 3D rendering.
Binding of antibodies to the spike (S)-protein of the SARS-CoV-2 virus is an essential  step for  developing immunity to the coronavirus.PDB 1igt. 3d rendering
Coronaviruses budding out of infected pneumocytes type II in a human lung. The darker cells are pneumocytes type I. 3d rendering
Multiple sclerosis (MS): microglia cells (orange) damage the myelin sheath of neuron axons leading to a loss of the nerve function. 3d rendering
Cancer cell being destroyed by cytotoxic T cells.
Natural killer cells are a type of lymphocytes which destroy cancer cells and other altered cells releasing cytotoxic granules. 3d rendering
Chromatin strand and isolated nucleosome.
Chromatin is a complex of DNA (yellow) and proteins (blue). Nucleosomes form the fundamental repeating units. Source: PDB entry 3afa. 3d rendering
RNA polymerase unwinds DNA strands (violet) and builds RNA (red) out of the nucleotides uridine, adenosine, cytlidine and guanosine monophosphate. Source: PDB entry 1i6h. 3d rendering
The gastric proton pump H+,K+-ATPase with a proton pump inhibitor (PPI) bound. It is a target for drugs that treat acid-related diseases. Source: PDB entry 5yIu. 3d rendering.
Migraine therapy: monoclonal antibodies block the CGRP-receptor. Calcitonin gene related peptide (yellow) can't bind to its receptor and lead to a widening of cerebral blood vessels, 3d rendering
Interleukin 4  bound to its receptor on a cell membrane. The IL-4 receptor consists of an alfa (light violet) and a gamma chain. Source: PDB entry 3bpl. 3d rendering
 ATP syntethase couples ATP (red) synthesis from ADP and inorganic phosphate (orange) to a proton gradient (yellow) created across the mitochondrial membrane during cellular respiration. 3d rendering
The nucleotide analog remdesivir is considered a promising antiviral drug  for the treatment of Sars-CoV-2 infections. It causes a decrease in viral RNA production. 2d rendering
树突状细胞呈现 T 淋巴细胞抗原。 抗原是来自肿瘤细胞,细菌或病毒的肽。 它们呈现抗原激活免疫反应的淋巴细胞。3d 渲染
Structure of a T-cell receptor bound to a cell membrane. The T-cell receptor activates the immune response to antigens in T-lymphocytes. 3d rendering
Insulin is a protein hormone that regulates the metabolism of carbohydrates and fats through the assimilation of glucose .Source: PDB entry 3I40. 3d rendering
Bacteriophages infecting and killing bacteria. Phages are a possible therapy against multi-drug-resistant bacteria. 3d rendering

PD-1  (red)  interacts with PD-L1 (yellow) from a antigen presenting cell leading to a down-regulation of the activating interaction of MHC-II (violet) with the T-cell receptor (blue). 3d rendering
Nucleosomes form the fundamental repeating units of eukaryotic chromatin. They consist of DNA wound around eight histone proteins and of about 146 base pairs. Source: PDB entry 3afa.3d rendering
内脏脂肪是高激素活性。 它提高血液中的 LDL 水平导致动脉粥样硬化和中风的风险较高。3d 渲染.
Massive diverticulosis.
Diverticula in the large intestine. Diverticulitis results of the inflammation of one of these diverticula. The most common sympton is abdominal pain. 3d rendering
LDL particles binding to LDL receptors on the cell membrane.
The binding of LDL particles to the LDL receptors mediates the endocytosis of the particles through clathrin coated vesicles. 3d rendering
After activation by an antigen presenting cell, a T helper cell segregates the cytokines IL-4, IL-5, IL-6, IL-9, IL-10 and IL-13.. Source: PDB entries 2B8U, 3VA2, 1ALU, 2H24, 3BPO. 3d rendering
Interleukin 4 (IL-4) molecules.
IL-4 is a cytokine and a key regulator of the immune system and plays an important role in allergic and asthmatic symptoms. Source PDB entry 2b8u. 3d rendering

Streptoccus bacteria.
Streptococcus species are responsible for pharyngitis, meningitis, bacterial pneumonia, endocarditis and necrotizing fasciitis. 3d rendering
共 5 页